There are many different puzzles in Resident Evil 2, and we will describe the. Green;; Dispersal Cartridge Lab Mixture Puzzle (Second Run): Blue, Red, Green,.

1. Resident Evil 2 Lab Chemical Puzzle
2. Resident Evil 2 Lab Cartridge Puzzle
3. Resident Evil 2 Remake Lab Puzzle

100% Completion Guide for Resident Evil 2 Remake.
Other RE2 Guides:

• All Endings.
• Beginner's Guide.
• All Mr Raccoons Locations.
• Lockers, Safe Codes / Combinations and Leon's Desk.
• The Tofu Survivor Bonus Mode (Characters / Unlocks).
• Weapon's Upgrades Location.
• Laboratory Puzzle Solution.
• Items / Keys Location.
• Weapon's Guide.

Puzzle Solutions

Click to enlarge...

Story Related

The achievements mentioned below are all story related so they can’t be missed.

Welcome to the city of the Dead

Make it to the police station. This achievement is unlocked right after you exit the gas station, just keep playing the game and rejoice your first one!

Path to the Goddess

Solve the Goddess Statue puzzle. This one requires you to get all 3 medallions and insert them at the statue located at the police station.

Never-Ending Rain

Escape the police station. You get this achievement after you go through the parking garage on to the 'Behind the RPD' section.

A Great Need for a Shower

Escape from the sewers. After the fight with 2G (William Birkin First appearence) your will be granted this achievement.

Endings and Difficulty

Achievements that you get by beating the game or certain stages several ways.

A Hero Emerges

Complete Leon's story. Beating the A or B campaign with Leon unlocks this.

A Heroine Emerges

Complete Claire's story. Beating the A or B campaign with Claire unlocks this.

Hack Complete

Complete Ada's segment. During Leon's campaign you get to control Ada, beating this segment unlocks this. Don't forget that you can also get the achievement called 'One Slick Super-Spy' while you play with Ada. For more information on how to get that achievement see the Misc section.

Hide and Seek

Complete Sherry's segment. During Leon's campaign you get to control Sherry, beating this segment unlocks this. Don't forget that you can also get the achievement called 'Youg Escape' while you play with Sherry. For more information on how to get that achievement see the Misc section.

Broken Umbrella

Witness the true ending. You get this achievement when you beat any B scenario. To unlock the ability to play on a B scenario you must play with Leon or Claire for the first time.

Leon 'S.' Kennedy

Complete Leon's story on 'Standard' or 'Hardcore' with an S rank. A S rank is get by beating the game within 3:30 hours in case you are playing an A scenario, or 3 hours in case you are playing a B scenario. That is true for the Standard difficulty because if you are crazy enough to do it on Hardcore mode, then the times are 2:30 hours for the A scenario and only 2 hours for the B one. Therefore the easiest way to do it is on Standard mode scenario A for Leon.

Sizzling Scarlet hero

Complete Claire's story on 'Standard' or 'Hardcore' with an S rank. A S rank is get by beating the game within 3:30 hours in case you are playing an A scenario, or 3 hours in case you are playing a B scenario. That is true for the Standard difficulty because if you are crazy enough to do it on Hardcore mode, then the times are 2:30 hours for the A scenario and only 2 hours for the B one. Therefore the easiest way to do it is on Standard mode scenario A for Claire.

Grim Reaper

Complete 'The 4th Survivor' extra mode. It unlocks when you beat a B scenario for Leon or Claire.

Hardcore Rookie

Complete Leon's story on 'Hardcore' game mode.

Hardcore College Student

Complete Claire's story on 'Hardcore' game mode.

Frugalist

Complete the game without using a recovery item. It is the easiest done in Assisted difficulty where the enemies are a little weaker and you recover a certain amount of health automatically.

Minimalist

Clear the game without opening the item box. Best done in Assisted difficulty where the enemies are a little weaker and you recover a certain amount of health automatically. If you pick up all of the Hip Pouches along the way that will help you a lot. Also if you unlocked any of the infinite weapons it will make your life easier.

A Small Carbon Footprint

Take 14000 steps or fewer in one playthrough. Doing a speedrun and getting a S rank of the game will naturally unlock this.

Bosses and Enemies

This section is dedicated to different ways to 'play” with the zombies.

Resident Evil 2 Lab Chemical Puzzle

Don't Need No Stinkin' Gun

Defeat an enemy with a knife. Don't need to be all knife hits to get this one, so you can shoot a zombie down to the floor and then hit him with the knife until you kill it.

Bon Appétit

Shoot the grenade you fed to an enemy. Equip a grenade as a defense item, then let a zombie grab you and press space to use it. Then step back and quickly shoot it to send him your regards and get the achievement.

Zombie Roundup

Kill 3 enemies at once with a sub-weapon. A good place to do this is in Jail with Leon when the cells are released. Just herd them and throw a grenade to get the achievement.

Like Skeet Shooting

Shoot a zombie dog or a licker out of the air. Best done with Leon's shotgun when you first encounter a zombie dog at the Parking Garage.

Keep Their Heads Ringin'

Paralyze a licker's sense of hearing. When you first encounter a licker use a flash grenade on him to stagger it and get the achievement.

Hats Off!

Shoot Tyrant's hat off his head. Just a single pistol shot will do, aim for his head and the achievement is yours.

Gotcha!

Defeat Stage 2 G using the crane only once. The fight against him is at the final part of the Sewers. Shoot him down 2 or 3 times to make sure that the first crane use is also his last. If he gets knocked down that means you got the achievement.

With Time to Spare

Defeat Stage 4 G with 4+ minutes left until detonation. This is in Claire's campaign, kill William Birkin as fast as possible outside the train car.

In The Blink of an Eye

Defeat Super Tyrant with 5+ minutes left until detonation. This is in Leon's campaign Mr. X in his final form will come at you, just down him as fast as possible. After receiving enough damage Ada will send you a rocket launcher to finish him off.

Collectibles

All the collectibles in the game can be found here.

Vermin Extermination

Destroy a Mr. Raccoon. First, go to the S.T.A.R.S. office like below picture:

Treasure Hunter

Using the photo hints, find 2 hidden items. First you need to get to the Workroom in the Sewers and get the roll film called 'Hiding Place'. Then you must head to the Dark Room back in the Police Station. Do not worry you will find a shortcut to it around the room where you found the roll film, assuming you have already the T-Bar Valve Handle. Once you reach it, reveal the film to get 2 pictures containing different places for you to loot, being those the Press Room, and the STARS Office. Do a quick search of the desks and you should get your rewards as well as this achievement.

Lore Explorer

Read all of the files.

Complete Vermin Extermination

Destroy all Mr. Raccoons. Read this guide.

Miscellaneous

Everything else that doesn’t fit into the other categories.

The Basics of Survival

Combine two items together. You can get this several ways like combining green herbs with red ones, or greens with greens, but interestingly most likely you will get it first by modding your pistol. See the achievement 'Customizer' for more details.

Hip to Add Squares

Increase your inventory slots. Done after you open the dial safe located at the West Office 1F that will provide you with the item needed. The code for it is as follows: 9left - 15right - 7left.
Also, You can increase your inventory slots by finding bag in below place:
As well, you can get next bag in below locker (code: NED (left) and MRG (right):

Customizer

Customize a weapon. Obtainable after you open the 'chest' locked by 2 dial locks at the West Office where the police is throwing a welcoming party dedicated to Leon. The code for the left lock is 'NED'; the one for the right lock is 'MRG'. After that combine the item with your pistol.

Eat This!

Counterattack with a sub-weapon. After you get your first defense item, let a zombie grab you and press space when the time is right to use it.

That'll Hold 'Em

Use Wooden Boards to board up a window. After you go through the Reception you will encounter a zombie banging on the window. Pick up some Wooden Boards just to your right and use them there to get the achievement.

A Vault-like Mind

Open a portable safe.

Resident Evil 2 Lab Cartridge Puzzle

Probably everyone has a different combination. If you have portable safe in your equip, click on buttons in correct sequence. Lights must to turn on green in the order shown in the picture below. Check which button lights which lamp (I prefer write it on the sheet of paper), then click on it in the correct order:

First Break-in

Open a dial safe. Gettable after you open any of the ones avaible throughout the game like the one at West Office. See 'Hip to Add Squares' achievement for more information.

A Waist of Space

Expand inventory slots to max.

One Slick Super-spy

Use only the EMF Visualizer to complete Ada's gameplay segment. Do not use the pistol or any sub weapons you may get or else you will fail to get the achievement.

Young Escape

Escape the bedroom within 60 seconds during Sherry's segment. Pick up the Stuffed Doll on the chair. Then examine it on your inventory, turn it arround and press Space. It will reveal a block that you need to insert at a puzzle near the door. Solve it and get the Scissors needed to cut yourself out of the bedroom.

Master of Unlocking

Open all of the safes and locks in the game. See the 'Tips' section of this guide for more information, where you will find all the safe and lock codes there are.

The Ghost Survivors DLC

Hell of a Sheriff

Complete the No Way Out scenario (No training mode). You unlock this mode when you complete all of the 3 previous ones: No Time To Mourn, Runaway and Forgotten Soldier. Watch the video below for a playthrough.

Got 'Em

Destroy all Mr. Raccoons hidden in The Ghost Survivors mode. Watch the video below for their locations.

This page contains every Resident Evil 2 (RE2) walkthrough for completing combinations, codes, or even solutions for every safe, dial lock, or similar code-input device.

It's important to note that all Resident Evil locker codes and safe combos stay the same across all variations of the Remake, so if you come to a locked safe early, you can use this page to cheat and get stuff out of sequence!

Resident Evil 2 Locker Codes and Safe Combos Quick Checklist[edit]

Want to see how to unlock all dial locks and safes, and other puzzle codes in Resident Evil 2 (RE2) at a glance? Check the list below for easy access, or read on further for more detailed information:

• Lion Statue Lock Solution - Lion, Leafy Branch, Bird
• Lion Statue Lock Solution (Second Run) - Crown, Torch, Bird
• Rookie's First Assignment Initials in West Office Solution - Left Lock: NED, Right Lock: MRG
• 3F Stairs Dial Lock (Letters) Solution - DCM (Found in a film roll).
• Unicorn Statue Lock Solution - Fish, Scorpion, Vase
• Unicorn Statue Lock Solution (Second Run) - Two People, Scales, Uncoiled Snake
• Men's Locker Room Dial Lock (Letters) Solution - CAP - Found in note in room attached to Operations Room.
• West Office Safe Solution - Left 9, Right 15, Left 7 - Found in S.T.A.R.S. Office memo.
• Maiden Statue Lock Solution - Woman, Bow, Snake
• Maiden Statue Lock Solution (Second Run) - Ram, Harp, Bird
• Waiting Room Safe Solution - Left 6, Right 2, Left 11 - Found in Confiscation Report File
• 'Sewer Locker' Control Room Dial Lock (Letters) Solution - SZF - Found in Jazz Festival Flyer
• Treatment Pool Room Safe Solution - Left 2, Right 12, Left 8 - Found on side of safe (lol!)
• Greenhouse Control Room Ladder Code 1 Solution - F, II, two small L shapes, and F - Found on ladder top
• Greenhouse Control Room Ladder Code (Second Run) - backwards L above dash, colon, F, II
• Greenhouse Control Room Drug Testing Code 2 Solution - Two small L shapes, I, a big square above a little square, and a thicker I
• Greenhouse Control Room Drug Testing Code (Second Run) - two small L shapes, I, tiny block above big square, colon

Lion Statue Lock Code[edit]

• Location: Main Hall
• Combination, Code, or Solution: Lion, Leafy Branch, Bird
• Second Run: Crown, Torch, Bird
• Contents: Lion Emblem

Leon's Desk Code for (Rookie's First Assignment) Dial Locks in West Office[edit]

• Location: West Office
• Combination, Code, or Solution: Left Lock: NED, Right Lock: MRG
• Contents: Leon: High-Capacity Magazine (Matilda), Claire: Speed Loader (SLS 60)

Safety Deposit Room Lock Control Panel (Missing Keys) Code[edit]

• Location: Safety Deposit Room
• Combination, Code, or Solution: On this control panel you can enter several codes, but you'll need the Spare Key 1 and Spare Key 2 to enter them all since the #2 and #3 button are missing.
• Contents: Since it’s a blank key, you can use it for either missing piece, which means installing it will either get you: Shotgun Shells/Flame Rounds and Gunpowder (2 key), or a Combat Knife (3 key). Finding both can get you the Hip Pouch.

3F Stairs Dial Lock (Letters) Code[edit]

• Location: Top of the Northwestern Stairs, 3F
• Combination, Code, or Solution: DCM (Found in a film roll).
• Contents: Leon: Magnum Ammo, Claire: Submachine Gun Ammo

Unicorn Statue Lock Code[edit]

• Location: Lounge
• Combination, Code, or Solution: Fish, Scorpion, Vase
• Second Run: Two People, Scales, Uncoiled Snake
• Contents: Unicorn Emblem

Men's Locker Room Dial Lock (Letters) Code[edit]

• Location: Men's Locker Room
• Combination, Code, or Solution: CAP - Found on whiteboard in room attached to Operations Room.
• Contents: Leon: Shotgun Shells, Claire: Flame Rounds

West Office Safe Code[edit]

• Location: West Office
• Combination, Code, or Solution: Left 9, Right 15, Left 7 - Found in S.T.A.R.S. Office memo.
• Contents:Hip Pouch 2

Maiden Statue Code[edit]

• Location: West Storage Room
• Combination, Code, or Solution: Woman, Bow, Snake (icons are obscured)
• Second Run: Ram, Harp, Bird
• Contents: Maiden Emblem

Resident Evil 2 Remake Lab Puzzle

Waiting Room Safe Code[edit]

• Location: Waiting Room
• Combination, Code, or Solution: Left 6, Right 2, Left 11 - Found in Confiscation Report File
• Contents: Leon: Muzzle Break for Matilda, Claire: High Capacity Mag for JMB Hp3

Sewer Locker Control Room Dial Lock (Letters) Code[edit]

• Location: Control Room, Sewer
• Combination, Code, or Solution: SZF - Found in Jazz Festival Flyer
• Contents: Leon: MAG Ammo, Claire: Submachine Gun Ammo

Treatment Pool Room Safe Code[edit]

• Location: Treatment Pool Room, Sewer
• Combination, Code, or Solution: Left 2, Right 12, Left 8 - Found on side of safe (lol!)
• Contents: Leon: Shotgun Stock for the W-870 Shotgun, Claire: Reinforced Frame for the SLS 60

Greenhouse Control Room Code 1 Solution[edit]

• Location: Greenhouse Control Room
• Combination, Code, or Solution: F, II, two small L shapes, and F - Found on ladder top
• Second Run: Backwards L above dash, colon, F, II
• Contents: Unlocks Ladder in Greenhouse to B2

Greenhouse Control Room Code 2 Solution[edit]

• Location: Greenhouse Control Room
• Combination, Code, or Solution: Two L’s, I, a big square above a little square, and a thicker I - Found on bottom of DNA Trophy
• Second Run: Two L's, I, tiny block above big square, colon
• Contents: Unlocks Dispersal Unit in Drug Testing Lab